The Results Are In

A huge thank you to everyone who took part in the process. Our priority setting partnership has agreed on the uncertainties based on the input from patients, carers, and healthcare professionals.

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JLA

The James Lind Alliance (JLA) is a non-profit making initiative, which was established in 2004. It brings patients, carers and clinicians together to identify and prioritise the top 10 uncertainties, or 'unanswered questions', about the effects of treatments that they agree are most important.

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DUETS

What is UK DUETs?
The UK Database of Uncertainties about the Effects of Treatments (UK DUETs) publishes treatment uncertainties from patients, carers, clinicians, and from research recommendations, covering a wide variety of health problems.

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Cochrane Group

The Cochrane Collaboration is an international organisation, and its business is to provide reliable information, not to offer practice or policy advice as if this could be applied universally. To help ensure that administered treatments do more good than harm, gaps in knowledge about their effects – uncertainties – must be identified, and those deemed sufficiently important must be addressed.

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Treatment Uncertainties Why is it important?

Patients and the public have a right to expect that research funders, researchers and health professionals are aware of uncertainties about the effects of treatments. Knowing about uncertainties tells us where further research is needed. Ignoring treatment uncertainties puts patients at risk. By making uncertainties known:

  • patients can see where evidence about the effects of treatments is lacking
  • researchers and research funders can take account of where their efforts and resources are needed.

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Uncertainties What does it mean?

The JLA definition of a treatment uncertainty is that:

 
  • no up-to-date, reliable systematic reviews of research evidence addressing the uncertainty about the effects of treatment exists
  • up-to-date systematic reviews of research evidence show that uncertainty exists

It can include other health care interventions, including prevention, testing and rehabilitation.


Prioritising Uncertainties Sorting and filtering

The questions that come in will be sorted and categorised by Neuro-Oncology JLA management staff (link) and then be prioritised by focussed groups and prioritised by the Neuro-Oncology Steering Group and Stakeholders to get "the 10 most important unanswered questions".