NCRI BRAIN CLINICAL PRIORITIES

The NCRI Brain Supportive and Palliative Care sub-group have adopted the JLA Clinical Priorities (1, 3, 4, 5, 7, 8, 9). Priorities 2, 6, and 10 are research priorities for the Imaging & Technological Development sub-group.

If you are interested in participating in research studies in any of these areas please contact us.

1 Do lifestyle factors (e.g. sleep, stress, diet) influence tumour growth in people with a brain or spinal cord tumour?
2 What is the effect on prognosis of interval scanning to detect tumour recurrence, compared with scanning on symptomatic recurrence, in people with a brain tumour?
3 Does earlier diagnosis improve outcomes, compared to standard diagnosis times, in people with a brain or spinal cord tumour?
4 In second recurrence glioblastoma, what is the effect of further treatment on survival and quality of life, compared with best supportive care?
5 Does earlier referral to specialist palliative care services at diagnosis improve quality of life and survival in people with a brain or spinal cord tumours?
6 Do molecular subtyping techniques improve treatment selection, prediction and prognostication in people with a brain or spinal cord tumour?
7 What are the long-term physical and cognitive effects of surgery and/or radiotherapy when treating people with a brain or spinal cord tumour?
8 What is the effect of interventions to help carers cope with changes that occur in people with a brain or spinal cord tumour, compared with standard care?
9 What is the effect of additional strategies for managing fatigue, compared with standard care, in people with a brain or spinal cord tumour?
10 What is the effect of extent of resection on survival in people with a suspected glioma of the brain or spinal cord?